深圳欣博盛生物科技有限公司 a1

TAK-385
货号:29512-1 mg 规格:1 mg 目录价:¥482
货号:29512-10 mg 规格:10 mg 目录价:¥3591
货号:29512-25 mg 规格:25 mg 目录价:¥7866
货号:29512-5 mg 规格:5 mg 目录价:¥2050
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TAK-385
别名:
Relugolix
产品描述:
A GnRHR antagonist (IC50s = 0.33 and 0.32 nM for the human and monkey receptors, respectively); selective for these receptors over the rat GnRHR receptor (IC50 = 9,800 nM), as well as a panel of 134 enzymes and receptors at 10 µM; 95-fold more potent at inhibiting GnRH-induced arachidonic acid release in CHO cells expressing human GnRHR compared with those expressing monkey GnRHR; decreases testis, ventral prostate, ovary, and uterus weight in human GNRHR knock-in mice at 3-200 mg/kg per day for 28 days; decreases plasma luteinizing hormone levels in castrated cynomolgus monkeys at 1 and 3 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
623.631666
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
737789-87-6
分子式:
C29H27F2N7O5S
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