深圳欣博盛生物科技有限公司 a1

TAU Antibody
品牌:ProSci LLC
货号:8077-0.02 mg 规格:0.02 mg 目录价:¥1345.5
货号:8077-0.1 mg 规格:0.1 mg 目录价:¥6084
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TAU Antibody
别名:
Microtubial-associated protein tau, MAPT, MAPTL, DDPAC, FTDP-17L, MSTD, MTBT1, MTBT2, PPND, PPP1R103
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
ELISA,WB,IHC-P
靶标/特异性:
TAU antibody is human, mouse and rat reactive. Multiple isoforms of TAU are known to exist; this antibody will only detect the two longest isoforms.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
TAU antibody is affinity chromatography purified via peptide column.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
TAU antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
TAU antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
The microtubial-associated protein TAU (MAPT), more commonly known as TAU, is is normally a highly soluble protein found predominantly in neurons (1), but accumulations of highly phosphorylated tau protein aggregates are observed in several neurodegenerative diseases including Alzheimer's disease, progressive supranuclear palsy, corticobasal degeneration, and frontotemporal lobar dementia. It was thought that these pathological tau aggregates were the toxic form of tau, but recent studies indicate that soluble and highly phosphorylated tau species are more closely associated with synaptic dysfunction and cell loss (2,3). Mutations in the TAU gene have also been associated with several of these neurodegenerative diseases (4).
Accession #:
NP_058519
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