TDO (Anopheles gambiae) (rec.) (His)-其他酶-深圳欣博盛生物科技有限公司

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TDO (Anopheles gambiae) (rec.) (His)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40T-0101-C050

规格：50 ug

目录价：￥4680

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TDO (Anopheles gambiae) (rec.) (His)

别名:

TPH2; TRPO; Tryptophan 2,3-dioxygenase; Tryptophan Oxygenase; Tryptophan Pyrrolase; Tryptophanase

产品描述:

Tryptophan 2,3-dioxygenase (TDO) is a heme-containing dioxygenase catalyzing the addition of molecular oxygen across the 2,3-double bond of the indole ring of tryptophan to form N-formylkynurenine (NFK). In Anopheles gambiae, TDO is the only enzyme able to catalyze the first and rate-limiting step in L-Trp catabolism through the kynurenine pathway. Tryptophan is an essential amino acid for protein synthesis and also the precursor for production of a number of neurotransmitters, such as serotonin and melatonin; in mosquitoes, the kynurenine pathway is essential for eye pigmentation. Conceivably, the tryptophan-using pathways should be regulated in a coordinated manner in mosquitoes as well as in other species and TDO activation/inactivation processes could play an essential role in these phenomena.

宿主来源:

Synthetic.

产品浓度:

0.5mg/ml (Lot specific)

保存温度:

-20°C

运输温度:

预期分子量:

~47.9kDa

产品形式:

liquid

存储溶液:

Liquid. In 50mM sodium phosphate pH 8.0, containing 0.15M sodium chloride, 0.2M imidazole and 10% glycerol.

产地:

瑞士

纯度:

>98% (SDS-PAGE)

生物活性:

Specific activity towards L-Trp: 87.0µmol/hr per mg. TDO catalyzes the oxidative opening of the L-tryptophan indole moiety to yield N-formylkynurenine (NFK).

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