Zmp1 (M. tuberculosis) (rec.) (His)-其他酶-深圳欣博盛生物科技有限公司

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Zmp1 (M. tuberculosis) (rec.) (His)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40T-0103-C050

规格：50 ug

目录价：￥4680

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Zmp1 (M. tuberculosis) (rec.) (His)

别名:

Zinc Metalloprotease 1; Endopeptidase; Rv0198c

产品描述:

M13 endopeptidases are single-pass, transmembrane zinc-metallopeptidases responsible in human for the regulation of the biological activity of many hormones and peptides and are involved in many important processes such as blood pressure regulation (Neprilysin or NEP1), cardiovascular development (Endothelin Converting Enzyme-1 or ECE-12), prevention of haemolytic reaction (KELL) and phosphate homeostasis (PHEX). Zmp1 is a soluble enzyme member of the M13 endopeptidases family that plays a key role in Mycobacterium tuberculosis pathogenicity with a still unknown mechanism. Recently, it was shown to suppress inflammasome activation by inhibiting caspase-1 activation, thus preventing processing of pro-IL-1beta into IL-1beta and the consequent phagosome maturation.

宿主来源:

E. coli

靶标/特异性:

Prefered cleavage sequence is PxxF.

产品浓度:

0.5mg/ml (Lot specific)

保存温度:

-20°C

运输温度:

预期分子量:

~73.9kDa

产品形式: