TEM4 antibody-多抗-深圳欣博盛生物科技有限公司

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TEM4 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX85426

规格：100μg

目录价：￥6200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TEM4 antibody

别名:

Rho guanine nucleotide exchange factor 17 , P164RHOGEF , RHOGEF17 , TEM4 , p164-RhoGEF

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ELISA, IHC-P, WB

靶标/特异性:

This antibody is specific for TEM4 Internal

同种型:

IgG

免疫原:

TEM4 antibody was raised against a 18 amino acid synthetic peptide near the center of human TEM4.The immunogen is located within amino acids 910 - 960 of TEM4.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

222

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.

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