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折扣/货期| 货号：GTX26393 | 规格：100μl | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Tenascin antibody [BC-24]
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, FCM, ICC/IF, IHC-Fr, IHC-P, RIA, WB
靶标/特异性:
The antibody recognizes an epitope within the N-terminal EGF-like (EGF-L) sequence of the molecule. It recognizes all human tenascin isoforms.
同种型:
IgG1
免疫原:
human tenascin.
克隆性:
Monoclonal
克隆号:
BC-24
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Ascites, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
Tenascin (TN)(Erickson and Bourdon 1989, Erickson 1993) is a high molecular weight, multifunctional, extracellular matrix glycoprotein, expressed in association with mesenchymal-epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors. It has been described under a variety of names: cytotactin, hexabrachion protein, J1-200/220, myotendinous antigen (MI), neuronectin (NEC1) and glioma mesenchymal extracellular matrix (GMEM). The TN molecule is a disulfide-linked hexamer. Human TN has 3 subunits of 190, 200 and 220 kD. It is primarily made up of 14.5 epidermal growth-factor-like repeats, 15 units similar to the fibronectin type-III-homology repeat and, at the C-terminus, has a sequence with homology to the globular domain of the beta and gamma chain of fibrinogen. Monoclonal antibody reacting specifically with tenascin is an essential tool for the localization, identification and studies on the role of the molecule in epithelial-mesenchymal and neuronal-glial interactions (Castellucci et al. 1991, Balza et al. 1993).
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