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折扣/货期| 货号：96-716 | 规格：0.05 mg | 目录价：￥14303.25 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TGF Beta 1 Recombinant Protein
别名:
TGFB1, CED, DPD1, LAP, TGFβ1 , TGF-beta
实验应用:
WB
表达系统:
HEK293 cells
保存温度:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
运输温度:
Blue Ice
产品形式:
Lyophilized
存储溶液:
TFA and acetonitrile
产地:
美国
生产商:
Prosci
功能与背景:
Transforming growth factor beta 1 (TGFB1) is also known as TGF-β1, CED, DPD1, TGFB. is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The TGFB1 protein helps control the growth and division (proliferation) of cells, the process by which cells mature to carry out specific functions (differentiation), cell movement (motility), and the self-destruction of cells (apoptosis). The TGFB1 protein is found throughout the body and plays a role in development before birth, the formation of blood vessels, the regulation of muscle tissue and body fat development, wound healing, and immune system function. TGFB1 is particularly abundant in tissues that make up the skeleton, where it helps regulate bone growth, and in the intricate lattice that forms in the spaces between cells (the extracellular matrix). Within cells, this protein is turned off (inactive) until it receives a chemical signal to become active. TGFB1 plays an important role in controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages. Most immune cells (or leukocytes) secrete TGFB1. TGFB1 has been shown to interact with TGF beta receptor 1, LTBP1, YWHAE, EIF3I and Decorin.
纯度:
>95% as determined by SDS-PAGE.
Less than 1.0 EU per ug by the LAL method.
Less than 1.0 EU per ug by the LAL method.
生物活性:
The bio-activity was determined by its ability to inhibit IL-4 induced HT-2 cell proliferation. The ED50<0. 05 ng/mL, corresponding to a specific activity of >2X107 Unit/mg
Accession #:
P01137-1
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