官网链接
折扣/货期| 货号：SIH-399-1MG | 规格：1 mg | 目录价：￥1137.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Thapsigargin
别名:
(3S,3aR,4S,6S,6AR,7S,8S,9bS)-6- (Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl octanoate
产品描述:
Autophagy inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
650.8
产品形式:
Colorless wax or white solid.
产地:
加拿大
功能与背景:
Thapsigargin is a cell-permeable inhibitor of the sarco-endoplasmatic reticulum Ca2+-ATPase (SERCA). This inhibition causes the release of intracellular Ca2+ stores. Thapsigargin also inhibits autophagy. This is due to the induction of and an ER stress response, which causes downstream effects that include an accumulation of autophagosomes in the cytosol. These intermediate structures never mature into amphisomes and autolysosomes, and the autophagy process cannot be completed.
纯度:
>98% (TLC); NMR (Conforms)
来源:
Synthetic
CAS号:
67526-95-8
分子式:
C34H50O12
溶解度:
Soluble in DMSO (65mg/mL); or Ethanol (20mg/mL)
PubChem CID:
446378
您可能感兴趣的产品
GAPDH antibody [GA1R]
货号：GTX82560
O-Carbamyl-D-serine
货号：20324
Benarthin
货号：20323
Ceramidastin, Bacterial ceramidase inhibitor
货号：19378
DDCAD < inhibitor of COMT, cyclic AMP phosphodiesterase and DOPA decarboxylase >
货号：18723
Pyridomycin, Antimycobacterial, Enoyl-ACP Reductase Inhibitor
货号：10080
Probestin, Aminopeptidase M Inhibitor, Aminopeptidase N Inhibitor
货号：367
STAT3-IN-12
货号：44651-10 mg
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询