深圳欣博盛生物科技有限公司 a1

TIM-1 antibody
货号:GTX85068 规格:100μg 目录价:¥6200
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TIM-1 antibody
别名:
hepatitis A virus cellular receptor 1 , CD365 , HAVCR , HAVCR-1 , KIM-1 , KIM1 , TIM , TIM-1 , TIM1 , TIMD-1 , TIMD1
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
ELISA, IHC-P, WB
同种型:
IgG
免疫原:
TIM-1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human TIM-1.The immunogen is located within amino acids 50 - 100 of TIM-1.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.
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