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折扣/货期| 货号：AG-40B-0180-3050 | 规格：3 x 50 ug | 目录价：￥5040 |
| 货号：AG-40B-0180-C050 | 规格：50 ug | 目录价：￥2520 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Tim-4 (mouse):Fc (human) (rec.)
别名:
TIM4; TIMD4; T Cell Immunoglobulin and Mucin Domain-containing Protein 4
产品描述:
Tim-4 (T cell immunoglobulin and mucin domain-containing protein 4) is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and TIM family. Tim-4 contains one Ig-like V-type (immunoglobulin-like) domain. It is expressed on dendritic cells and macrophages. TIM4 is expressed solely on antigen presenting cells (APCs) and is not found on T cells in contrast to TIM1 and TIM3. Tim-4 has a short intracellular domain and lacks an inward signaling motif. Tim-4 plays an important role in the proliferation of T helper type 2 (Th2) cells. Tim-4 binds to phosphatidylserine (PS) on the surface of apoptotic cells in a calcium-dependent manner and mediates phagocytosis of apoptotic cells.
宿主来源:
HEK 293 cells
产品浓度:
1mg/ml after reconstitution
保存温度:
+4°C
运输温度:
BI
预期分子量:
~110kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
生物活性:
Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells.
内毒素水平:
<0.01EU/µg purified protein (LAL test).
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