Tissue factor pathway inhibitor 2 Antibody / TFPI2-单抗-深圳欣博盛生物科技有限公司

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Tissue factor pathway inhibitor 2 Antibody / TFPI2

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V5813SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

Tissue factor pathway inhibitor 2 Antibody / TFPI2

产品描述:

The extrinsic pathway of blood coagulation is initiated by contact of plasma factor VII with tissue factor, a cellular membrane glycoprotein that normally is segregated from the bloodstream but can be exposed after tissue injury or newly synthesized in endothelial cells or leukocytes after stimulation by endotoxin and cytokines. Inhibition of Factor VIIa tissue factor activity requires a plasma component (tissue factor pathway inhibitor (TFPI), lipoprotein-associated coagulation inhibitor (LACI) or extrinsic pathway inhibitor (EPI)) and factor Xa. TFPI directly inhibits factor Xa, and, in an Xa-dependent fashion, also inhibits the Factor VIIa tissue factor catalytic complex. TFPI is a multivalent, Kunitz-type proteinase inhibitor that circulates in association with plasma lipoproteins VLDL, LDL, and HDL. TFPI-2 (also known as placental protein 5) is a related glycoprotein that was originally isolated from human placenta.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P, WB

同种型:

Mouse IgG1, kappa

免疫原:

A portion of amino acids 100-235 from human TFPI2 protein was used as the immunogen for the Tissue factor pathway inhibitor 2 antibody.

克隆性:

Monoclonal (mouse origin)