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折扣/货期| 货号：GTX53028 | 规格：50μg | 目录价：￥8000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TNF Receptor II antibody [4G22]
别名:
CD120b , TBPII , TNF receptor superfamily member 1B , TNFBR , TNFR1B , TNFR2 , TNFR75 , TNFR80 , TNFRII , TNFRSF1B , p75 , p75TNFR , TNF receptor II
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-Fr, WB
同种型:
IgG2
免疫原:
Human recombinant TNFRSF1B EC domain
克隆性:
Monoclonal
克隆号:
4G22
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
48
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
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