TP53/p53 CUTANA™ CUT&RUN Antibody-CUTANA™ CUT&RUN Antibodies-深圳欣博盛生物科技有限公司

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TP53/p53 CUTANA™ CUT&RUN Antibody

品牌：EpiCypher

官网链接

说明书

折扣/货期

货号：13-2015

规格：100 µL

目录价：￥5985

产品详情

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产品名称:

TP53/p53 CUTANA™ CUT&RUN Antibody

产品描述:

This antibody meets EpiCypher’s “CUTANA Compatible” criteria for performance in Cleavage Under Targets and Release Using Nuclease (CUT&RUN) and/or Cleavage Under Targets and Tagmentation (CUT&Tag) approaches to genomic mapping. Every lot of a CUTANA Compatible antibody is tested in the indicated approach using EpiCypher optimized protocols (epicypher.com/protocols) and determined to yield peaks that show a genomic distribution pattern consistent with reported function(s) of the target protein. TP53/p53 acts as a tumor suppressor by promoting growth arrest or apoptosis and is mutated in over 50% of cancers. It forms a complex with NF-Y, which binds to CCAAT box-containing promoters [1].TP53/p53 antibody produces CUT&RUN peaks above background primarily in promoter regions (Figure 1) that are enriched with known TP53/p53 DNA-binding motifs (Figure 2).

反应种属:

Human

宿主来源:

Rabbit

实验应用:

CUT&RUN, IP, WB

免疫原:

Between amino acids 325 and 375

克隆性:

Polyclonal

保存温度:

Stable for 1 year at 4°C from date of receipt