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折扣/货期| 货号：AG-40B-0071-3050 | 规格：3 x 50 ug | 目录价：￥4320 |
| 货号：AG-40B-0071-C050 | 规格：50 ug | 目录价：￥2160 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TRAIL-R2 (human):Fc (human) (rec.)
别名:
DR5; TNFRSF 10B; CD262; Tumor Necrosis Factor Receptor Superfamily Member 10B; TRAIL Receptor 2
产品描述:
TRAIL-R2 (DR5; CD262) is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
宿主来源:
HEK 293 cells
靶标/特异性:
Binds to human and mouse TRAIL.
产品浓度:
1mg/ml after reconstitution
保存温度:
+4°C
运输温度:
BI
预期分子量:
~50kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
生物活性:
Blocks human or mouse TRAIL activity in a concentration of 1-10µg/ml.
内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
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