Translin antibody-多抗-深圳欣博盛生物科技有限公司

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Translin antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX31440

规格：100μg

目录价：￥6200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Translin antibody

别名:

translin , BCLF-1 , C3PO , RCHF1 , REHF-1 , TBRBP , TRSLN

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

ELISA, IHC-P, WB

靶标/特异性:

At least two isoforms of Translin are known to exist; this antibody will detect both.

同种型:

IgG

免疫原:

Translin antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human Translin.The immunogen is located within the last 50 amino acids of Translin.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

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