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折扣/货期| 货号：GTX28293 | 规格：100μg | 目录价：￥4300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Troponin I skeletal muscle antibody [12F10]
别名:
troponin I2, fast skeletal type , AMCD2B , DA2B , FSSV , fsTnI
反应种属:
Human
宿主来源:
Mouse
实验应用:
Purification, WB
靶标/特异性:
Cross-reaction with cardiac TnI is less than 0.05%.
同种型:
IgG2b
免疫原:
Human skTnI
克隆性:
Monoclonal
克隆号:
12F10
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
预期分子量:
21
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
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