UBE3A antibody [HL1660]-单抗-深圳欣博盛生物科技有限公司

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UBE3A antibody [HL1660]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX637258	规格：100μl	目录价：￥4000
货号：GTX637258-S	规格：25μl	目录价：￥1700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

UBE3A antibody [HL1660]

别名:

ubiquitin protein ligase E3A , ANCR , AS , E6-AP , EPVE6AP , HPVE6A

反应种属:

Human

宿主来源:

Rabbit

实验应用:

同种型:

IgG

免疫原:

Recombinant protein encompassing a sequence within the center region of human UBE3A. The exact sequence is proprietary.

克隆性:

Monoclonal

克隆号:

HL1660

纯化方式:

Affinity purified by Protein A.

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, no preservatives.

生产商:

GeneTex

功能与背景:

This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

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