| 货号:57-994 | 规格:400 ul | 目录价:¥8687.25 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
VDR Antibody
别名:
Vitamin D3 receptor, VDR,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR, NR1I1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB,Flow
同种型:
Rabbit Ig
克隆性:
Polyclonal
纯化方式:
This antibody is purified through a protein A column, followed by peptide affinity purification.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Supplied in PBS with 0.09% (W/V) sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
This gene encodes the nuclear hormone receptor for vitamin
D3. This receptor also functions as a receptor for the secondary
bile acid lithocholic acid. The receptor belongs to the family of
trans-acting transcriptional regulatory factors and shows sequence
similarity to the steroid and thyroid hormone receptors. Downstream
targets of this nuclear hormone receptor are principally involved
in mineral metabolism though the receptor regulates a variety of
other metabolic pathways, such as those involved in the immune
response and cancer. Mutations in this gene are associated with
type II vitamin D-resistant rickets. A single nucleotide
polymorphism in the initiation codon results in an alternate
translation start site three codons downstream. Alternative
splicing results in multiple transcript variants encoding the same
protein.
Accession #:
P11473
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