VEGFD Recombinant Protein-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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VEGFD Recombinant Protein

品牌：ProSci LLC

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说明书

折扣/货期

货号：96-777

规格：0.1 mg

目录价：￥10986.3

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

VEGFD Recombinant Protein

别名:

FIGF, VEGFD

实验应用:

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

PBS, pH7.4

产地:

美国

生产商:

Prosci

功能与背景:

Vascular endothelial growth factor D (VEGF-D) is also known as C-fos induced growth factor (FIGF), which belongs to the PDGF / VEGF growth factor family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. This secreted protein VEGF-D / FIGF undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3. The structure and function of this protein is similar to those of VEGFC. FIGF / VEGF-D is highly expressed in lung, heart, small intestine and fetal lung. FIGF / VEGF-D may function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR / FLK1) and VEGFR-3 (FLT4) receptors.

纯度:

>95% as determined by SDS-PAGE.

生物活性:

The bioactivity was measured by its ability to stimulate the cell proliferation of human microvascular endothelial cells (HMVECs). The ED50 for this effect is typically 50‑200 ng/mL.

Accession #:

AAH27948

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