深圳欣博盛生物科技有限公司 a1

Verdinexor
货号:26171-1 mg 规格:1 mg 目录价:¥429
货号:26171-10 mg 规格:10 mg 目录价:¥2720
货号:26171-5 mg 规格:5 mg 目录价:¥1769
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Verdinexor
别名:
KPT-335
产品描述:
An inhibitor of XPO1/CRM1 with anticancer and antiviral activities; inhibits the growth of OCI-Ly3, OCI-Ly10, and CLBL1 DLBCL cells (IC50s = 2.1, 41.8, and 8.5 nM, respectively); inhibits XPO1/CRM1-mediated nuclear transport of RSV M protein at >1 μM; reduces RSV A2 replication (IC50 = 0.96 μM) without affecting viability of A549 cells (CC50 = >38 μM); reduces virus shedding, pulmonary TNF-α, IL-6, MCP01, and IFN-γ expression, and leukocyte infiltration into the bronchoalveolar space in a mouse model of influenza A viral infection at 20 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
442.318139
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1392136-43-4
分子式:
C18H12F6N6O
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