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折扣/货期| 货号：26170-10 mg | 规格：10 mg | 目录价：￥2251.2 |
| 货号：26170-25 mg | 规格：25 mg | 目录价：￥5252.8 |
| 货号：26170-5 mg | 规格：5 mg | 目录价：￥1206 |
| 货号：26170-50 mg | 规格：50 mg | 目录价：￥9326.4 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TAK-715
产品描述:
An inhibitor of p38α MAPK (IC50 = 7.1 nM); selective for p38α over p38β (IC50 = 200 nM), as well as over p38γ/δ, JNK, ERK1, IKKβ, MEKK1, and TAK1 (IC50 = >10 µM for all) but also inhibits CK1δ and CK1ε; inhibits LPS-induced TNF-α release from THP-1 cells (IC50 = 48 nM); LPS-induced TNF-α production by 87.6% in mice at 10 mg/kg; reduces adjuvant-induced paw swelling in a rat model of rheumatoid arthritis at 30 mg/kg; inhibits Wnt3a-induced phosphorylation of hDvl2 in a p38α-independent manner
保存温度:
-20
运输温度:
-20
预期分子量:
399.50916
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
303162-79-0
分子式:
C24H21N3OS
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