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折扣/货期| 货号：28453-1 mg | 规格：1 mg | 目录价：￥1273 |
| 货号：28453-10 mg | 规格：10 mg | 目录价：￥6218 |
| 货号：28453-5 mg | 规格：5 mg | 目录价：￥4047 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Vicriviroc (maleate)
别名:
SCH 417690
产品描述:
A CCR5 antagonist (Ki = 2.5 nM); selectively inhibits CCR5 over M1 and M2 muscarinic acetylcholine receptors (Kis = >10,000 nM for both) and hERG potassium channels (IC50 = 5.8 µM); decreases CCL3-induced chemotaxis of Ba/F3 cells expressing recombinant human CCR5 (IC50 = 0.91 nM); inhibits the replication of 30 R5-tropic HIV-1 clinical isolates in PMBCs (EC50s = 0.04-1.4 nM) and reduces viral entry of seven drug-resistant strains of HIV-1 in U87 cells expressing CD4 and CCR5 (EC50s = 8.7-32.9 nM)
保存温度:
-20
运输温度:
-20
预期分子量:
533.629029
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
599179-03-0
分子式:
C28H38F3N5O2 • C4H4O4
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