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折扣/货期| 货号：28454-10 mg | 规格：10 mg | 目录价：￥2693 |
| 货号：28454-25 mg | 规格：25 mg | 目录价：￥5883 |
| 货号：28454-5 mg | 规格：5 mg | 目录价：￥1501 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ZK 756326 (hydrochloride)
产品描述:
A non-peptide agonist of CCR8; inhibits binding of CCL1 to human CCR8 (IC50 = 1.8 µM); stimulates extracellular acidification in cells expressing human and mouse CCR8 (EC50s = 254 nM and 2.6 µM, respectively); exhibits >28-fold selectivity for CCR8 over 26 other GPCRs; binds to the serotonergic receptors 5-HT1A, 5-HT2B, 5-HT2C, and 5-HT5A (IC50s = 5.4, 4.4, 34.8, and 16 µM, respectively); induces Gαi-mediated calcium mobilization, ERK phosphorylation, exhibits leukocyte chemotactic activity, and inhibits HIV fusion of cells expressing CD4 and CCR8
保存温度:
-20
运输温度:
-20
预期分子量:
356.4587
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1780259-94-0
分子式:
C21H28N2O3 • 2HCl
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