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折扣/货期| 货号：SIH-567-20MG | 规格：20 mg | 目录价：￥748.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Vildagliptin
别名:
(S)-1-[N-(3-hydroxy-1-adamantyl)glycyl]pyrrolidine-2-carbonitrile; LAF237
产品描述:
Anti-diabetic agent
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
303.4
产品形式:
White powder
产地:
加拿大
功能与背景:
Vildagliptin is a potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that cleaves glucagon-like peptide 1 (GLP-1) (1). Delaying the degradation of GLP-1 extends the action of insulin and suppresses the release of glucagon which results in reduction in elevated blood glucose levels (hyperglycemia) (2). It is a clinically useful antidiabetic agent. Ameliorates cognitive deficits in streptozotocin-induced Alzheimers disease model (3). Displays protective effects on βcells by inhibition of ER stress in a mouse model (4). Clinically useful antidiabetic agent.
纯度:
>98% (HPLC); NMR (Conforms)
来源:
Synthetic
CAS号:
274901-16-5
分子式:
C17H25N3O2
溶解度:
May be dissolved in DMSO (45 mg/ml); or DMF (20 mg/ml); or ethanol (20 mg/ml)
PubChem CID:
11077541
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