深圳欣博盛生物科技有限公司 a1

VIP (human, porcine, rat, ovine) (trifluoroacetate salt)
货号:24996-1 mg 规格:1 mg 目录价:¥3229.4
货号:24996-500 µg 规格:500 µg 目录价:¥1715.2
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
VIP (human, porcine, rat, ovine) (trifluoroacetate salt)
别名:
Vasoactive Intestinal Peptide
产品描述:
A 28-amino acid peptide that has roles as a hormone and neurotransmitter and has diverse biological activities; a VPAC1 and VPAC2 agonist (EC50s = 3 and 8 nM, respectively, in CHO cell membranes expressing the recombinant human receptors); selective for these receptors over PAC1 (Ki = 500-1,000 nM in radioligand binding assays); induces relaxation of carbachol-precontracted isolated human fundus or antrum circular smooth muscle strips from 10-300 nM; reduces pentagastrin-induced increases in gastric acid secretion and mucosal blood flow in conscious dogs at 8 µg/kg; decreases serum and peritoneal lavage levels of TNF-α and IL-6 and reduces mortality in a mouse model of LPS-induced endotoxemia from 5-10 nM; inhibits SARS-CoV-2 replication in Calu-3 human lung epithelial cells and isolated human peripheral blood monocytes at 5 nM; inhibits production of IL-6, IL-8, and TNF-α in SARS-CoV-2-infected Calcu-3 cells
保存温度:
-20
运输温度:
-20
预期分子量:
3325.79998
产品形式:
A lyophilized powder
纯度:
≥95%
分子式:
C147H238N44O42S • XCF3COOH
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