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折扣/货期| 货号：37299-10 mg | 规格：10 mg | 目录价：￥2399 |
| 货号：37299-25 mg | 规格：25 mg | 目录价：￥5641 |
| 货号：37299-5 mg | 规格：5 mg | 目录价：￥1260 |
| 货号：37299-50 mg | 规格：50 mg | 目录价：￥9996 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
VU0134992 (hydrochloride)
产品描述:
An inhibitor of Kir4.1 (IC50 = 5.2 µM in a thallium flux assay); selective for Kir4.1 over Kir2.3, Kir7.1, and SUR1/Kir6.2 (IC50s = 13.2, 34.2, and 11.4 µM, respectively), as well as Kir1.1, Kir2.1, and Kir2.2 at 30 µM; inhibits Kir4.2, heteromeric GIRK1/GIRK2, and heteromeric GIRK1/GIRK4 (IC50s = 8.1, 2.5, and 3.1 µM, respectively); reduces polymyxin B-induced decreases in cell viability in HK-2 cells and prevents polymyxin B-induced increases in apoptosis in mouse embryonic kidney explant cultures at 5 µM; increases urine volume and urinary sodium and potassium levels in rats at 50 and 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
411.37642
产品形式:
A solid
纯度:
≥95%
分子式:
C20H31BrN2O2 • XHCl
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