WISP1 blocking peptide-封闭肽-深圳欣博盛生物科技有限公司

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WISP1 blocking peptide

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX88924-PEP

规格：100μg

目录价：￥3200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

WISP1 blocking peptide

别名:

Wnt1 Inducible Signaling Pathway Protein 1 , Ccn4 , Wisp1-Ot1 , Wisp1-Ut1 , Wisp1C , Wisp1I , Wisp1Tc , Wisp1

靶标/特异性:

The peptide was used in the production of GTX88924.

克隆号:

产品浓度:

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Lyophilized powder

存储溶液:

Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.

生产商:

GeneTex

功能与背景:

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-media

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