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折扣/货期| 货号：30062-10 mg | 规格：10 mg | 目录价：￥2479 |
| 货号：30062-25 mg | 规格：25 mg | 目录价：￥5842 |
| 货号：30062-5 mg | 规格：5 mg | 目录价：￥1461 |
| 货号：30062-50 mg | 规格：50 mg | 目录价：￥10961 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
WZ8040
产品描述:
An inhibitor of mutant EGFR (IC50s = 2-306 in Ba/F3 cells); selective for EGFR mutants, including the EGFRDel E746_A750 and EGFRL858R mutations conferring gefitinib sensitivity and the EGFRDel E746_A750/T790M mutation conferring gefitinib resistance (IC50s = 2, 6, and 6 nM in Ba/F3 cells), over wild-type EGFR (IC50 = 1,820 nM in HN11 cells); inhibits ERBB2Ins G776V,C and wild-type ERBB2 (IC50s = 20 and 32 nM, respectively, in Ba/F3 cells); inhibits proliferation of PC-9 cells harboring the EGFRDel E746_A750 mutation and gefitinib-resistant PC-9 GR cells harboring the EGFRT790M resistant allele (EC50s = 6 and 8 nM, respectively)
保存温度:
-20
运输温度:
-20
预期分子量:
481.01384
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1214265-57-2
分子式:
C24H25ClN6OS
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