| 货号:24906-1 mg | 规格:1 mg | 目录价:¥442.2 |
| 货号:24906-10 mg | 规格:10 mg | 目录价:¥3296.4 |
| 货号:24906-25 mg | 规格:25 mg | 目录价:¥6552.6 |
| 货号:24906-5 mg | 规格:5 mg | 目录价:¥1755.4 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
XL413 (hydrochloride)
产品描述:
A potent inhibitor of Cdc7 (IC50 = 3.4 nM); >60, >10, and >300-fold selective for Cdc7 over CK2, PIM1, and a panel of over 100 protein kinases, respectively; inhibits the growth of MDA-MB-231T and COLO 205 cells (IC50s = 118 and 140 nM, respectively); inhibits Cdc7-specific phosphorylation of MCM2 and induces cell cycle accumulation in the S and G2 phases in MDA-MB-231T and COLO 205 cells; inhibits MCM2 phosphorylation (ED50 = <3 mg/kg) and reduces tumor growth in a COLO 205 mouse xenograft model at 10, 30, and 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
326.17744
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
2062200-97-7
分子式:
C14H12ClN3O2 • HCl
促销活动
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