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折扣/货期| 货号：AG-48B-1000-KI01 | 规格：96 wells | 目录价：￥7320 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Zinc-alpha-2-glycoprotein (human) TurboELISA™ Kit
别名:
Zn-alpha-2-GP; Zn-alpha-2-Glycoprotein; ZAG; ZA2G; AZGP1; ZNGP1
产品描述:
This assay is a less than 1 hour sandwich Enzyme Linked-Immunosorbent Assay (ELISA) for quantitative determination of human Zinc-alpha-2-glycoprotein in biological fluids. Zinc-alpha-2-glycoprotein (ZAG) was first identified in the 1960s, and it's name derives from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in a range of body fluids. ZAG is identical to a lipid mobilizing factor isolated from the urine of patients with cancer cachexia and stimulates lipolysis in in vitro and in vivo experiments. Due to its expression in, and secretion from adipocytes, ZAG is considered an adipokine. Recently, the clinical significance of ZAG has been clarified. ZAG expression in adipocytes is inversely related to fat mass, thus it is intimately involved in the maintenance of body weight in mice and humans. Epidemiological studies have uncovered an association between ZAG and plasma cholesterol. The non-synonymous single nucleotide polymorphism rs4215 in ZAG is associated with plasma cholesterol and obesity. Structurally ZAG possesses a class I major histocompatibility complex (MHC) protein fold. It is distinct from other members of this protein family in that it is soluble, rather than being anchored to plasma membranes, and it associates with prolactin inducible protein rather than beta2-microglobulin. Similar to peptide antigen-presenting class I MHC molecules, ZAG possesses an open apical groove between its alpha1 and alpha2 domain helices.
靶标/特异性:
Detects human Zinc-alpha-2-glycoprotein. Does not detect mouse Zinc-alpha-2-glycoprotein.
保存温度:
+4°C
运输温度:
BI
产地:
瑞士
灵敏度:
0.23 ng/ml
检测范围:
0.9375 to 60 ng/ml
检测方法:
Colorimetric
样本类型:
Cell Culture Supernatant, Plasma, Serum
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