深圳欣博盛生物科技有限公司 a1

15 deoxy Delta 12,14 Prostaglandin J2 antibody
货号:GTX22313 规格:50μl 目录价:¥5300
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
15 deoxy Delta 12,14 Prostaglandin J2 antibody
别名:
Prostaglandin J2
反应种属:
Species independent
宿主来源:
Rabbit
实验应用:
ELISA, RIA
靶标/特异性:
This antibody detects Prostaglandin J2 (25.3 %), Prostaglandin D2 (13.13 %), D12-Prostaglandin J2 (8.89 %) and 9a,11b-Prostaglandin F2 alpha (6.93 %).
同种型:
IgG
免疫原:
15-deoxy-D12,14-Prostaglandin J2 conjugated to a protein carrier molecule
克隆性:
Polyclonal
克隆号:
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
15-deoxy-Delta12,14-Prostaglandin J2 (15-d-PGJ2) is one of the ultimate dehydration products of PGD2, formed via the intermediate Delta12-PGJ2. 15-d-PGJ2 is physiologically present in body fluids at concentration of 10-12 to 10-9 M, but increases dramatically under stress such as infection and inflammation. 15-d-PGJ2 exerts both pro- and anti-inflammatory effects in a cell-type and concentration-dependent manner, with many of these effects mediated via binding to the gamma isoform of the peroxisome proliferators-activated receptor (PPAR-gamma). 15-d-PGJ2 appears to induce HO-1 expression by a PPAR-gamma-independent mechanism mediated by the generation of reactive oxygen species (ROS).
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