| 货号:GTX44869 | 规格:50μg | 目录价:¥6100 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
A2BP1 antibody, Internal
别名:
RNA binding fox-1 homolog 1 , 2BP1 , A2BP1 , FOX-1 , FOX1 , HRNBP1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
A synthetic peptide corresponding to an Internal region of Human A2BP1
克隆性:
Polyclonal
克隆号:
纯化方式:
Affinity Purified
偶联:
Unconjugated
产品浓度:
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 2% Sucrose, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
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