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折扣/货期| 货号：GTX22803 | 规格：200μl | 目录价：￥5600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AChE antibody [HR2]
别名:
acetylcholinesterase (Cartwright blood group) , ACEE , ARACHE , N-ACHE , YT
反应种属:
Bovine, Cat, Guinea pig, Human, Mouse, Rabbit
宿主来源:
Mouse
实验应用:
ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
靶标/特异性:
This antibody does not cross react with rat or frog AChE, and does not detect butyrylcholinesterase (BChE). Immunohistochemical staining of AChE in human brain samples with GTX22803 results in staining of nerve fibers and terminals.
同种型:
IgG2b
免疫原:
Purified human cerebellar acetylcholinesterase.
克隆性:
Monoclonal
克隆号:
HR2
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
68
产品形式:
Liquid
存储溶液:
PBS, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008]
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