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折扣/货期| 货号：GTX22804 | 规格：100μl | 目录价：￥5600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AChR antibody [88B]
别名:
cholinergic receptor nicotinic delta subunit , cholinergic receptor nicotinic gamma subunit , ACHRD , CMS2A , CMS3A , CMS3B , CMS3C , FCCMS , SCCMS , ACHRG
反应种属:
Amphibians, Chicken, Fish, Human, Mouse, Rabbit, Rat
宿主来源:
Mouse
实验应用:
ELISA, ICC/IF, IHC-Fr, IHC-P, IP, WB
靶标/特异性:
This antibody detects nicotinic acetylcholine receptor (nAChR) gamma and delta subunits. This antibody does not detect the alpha 1 and beta 1 subunits.
同种型:
IgG1
免疫原:
Purified Torpedo californica acetylcholine receptor.
克隆性:
Monoclonal
克隆号:
88B
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Ascites, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
Acetylcholine receptors (AChRs) mediate synaptic transmission at the neuromuscular junction. The channel-linked AChR that mediates rapid, excitatory actions of acetylcholine is called nicotinic AChR (nAChR) because it can be activated by nicotine. The non-channel linked AChR that medicates the slow actions of acetylcholine, which can be either inhibitory or excitatory, is called muscarinic AChR (mAChR) because it can be activated by muscarine. The nAChRs fall into two subclasses, the muscle-type and the neuronal-type. The muscle-type receptor is a pentameric glycoprotein of five membrane spanning subunits, (2 alpha 1’s, beta 1, gamma or epsilon and delta) which form a ligand gated ion channel. The neuronal nAChR is also a pentamer, but unlike the muscle-type, is made up of only two general types of subunits, alpha and beta of which multiple subtypes have been described (alpha 2 to alpha 8 and beta 2 to beta 4).
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