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折扣/货期| 货号：GTX31779-PEP | 规格：50μg | 目录价：￥2400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Activin Receptor Type IA blocking peptide
别名:
Activin A Receptor Type 1 , Actri , Acvr1A , Acvrlk2 , Alk2 , Fop , Skr1 , Tsri , Acvr1
产品描述:
Activin Receptor Type IA peptide is used for blocking the activity of Activin Receptor Type IA antibody (catalog number GTX31779).
实验应用:
Neutralizing /Inhibition
克隆号:
偶联:
Unconjugated
产品浓度:
200 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
PBS, 0.1% BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008]
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