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折扣/货期| 货号：GTX52509 | 规格：100μg | 目录价：￥8000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Activin Receptor Type IIA antibody [6J16]
别名:
ACTRII , ACVR2 , ACVR2A , activin A receptor type 2A , Activin Receptor Type IIA , Activin A Receptor type IIA
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P, WB
靶标/特异性:
This antibody was selected for its ability to detect human Activin Receptor type IIA. No cross reactivity was found to Activin RI and RIIB
同种型:
IgG2
免疫原:
Recombinant Activin RIIA extra cellular domain
克隆性:
Monoclonal
克隆号:
6J16
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
200 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
58
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]
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