深圳欣博盛生物科技有限公司 a1

ADAMTS4 antibody
货号:GTX78143 规格:25μg 目录价:¥3800
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ADAMTS4 antibody
别名:
ADAM metallopeptidase with thrombospondin type 1 motif 4 , ADAMTS2 , ADAMTS4 , ADMP1 , ADAMTS-4
反应种属:
Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Human, Monkey, Mouse
宿主来源:
Rabbit
实验应用:
IHC-P
同种型:
IgG
免疫原:
Synthetic 15 amino acid peptide from Disintegrin-like domain of human ADAMTS4.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradation of aggrecan. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
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