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折扣/货期| 货号：GTX04561 | 规格：100μl | 目录价：￥7800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Adenosine A2a Receptor antibody [7F6-G5-A2]
别名:
adenosine A2a receptor , A2aR , ADORA2 , RDC8
反应种属:
Dog, Guinea pig, Human, Mouse, Pig, Rabbit, Rat, Sheep
宿主来源:
Mouse
实验应用:
CyTOF, FCM, ICC/IF, IHC-Fr, IHC-P, WB
同种型:
IgG2a
免疫原:
Full length recombinant human Adenosine A2a R(UniProt# P29274). Epitope mapped to SQPLPGER in the third intracellular loop (PMID 9822147).
克隆性:
Monoclonal
克隆号:
7F6-G5-A2
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
45
产品形式:
Liquid
存储溶液:
PBS, 0.02% sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]
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