| 货号:GTX10346 | 规格:125μg | 目录价:¥5600 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
AKAP12 antibody
别名:
A-kinase anchoring protein 12 , AKAP12A , AKAP12B , AKAP12G
反应种属:
Rat
宿主来源:
Sheep
实验应用:
IP, WB
同种型:
IgG
免疫原:
rat SSeCKS.
克隆性:
Polyclonal
克隆号:
纯化方式:
IgG fraction
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.08% Sodium azide.
生产商:
GeneTex
功能与背景:
SSeCKS (Src Suppressed C Kinase Substrate) is a major protein kinase C substrate with tumor suppressor activity in models of src- and ras-induced oncogenic transformation. SSeCKS regulates actin-based cytoskeletal and tissue architecture, as well as kinases such as protein kinase C (PKC), protein kinase A (PKA) and calmodulin. Additionally, SSeCKS, has been implicated in the formation of migratory processes and cell migration during embryogenesis. Rat SSeCKS shares extensive homology with human Gravin, an autoantigen in myasthenia gravis that encodes kinase scaffolding functions and whose expression pattern in fibroblasts and nerves suggests a role in cell motility.
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