ALDH2 antibody, Internal-多抗-深圳欣博盛生物科技有限公司

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ALDH2 antibody, Internal

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX88073

规格：100μg

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

ALDH2 antibody, Internal

别名:

aldehyde dehydrogenase 2 family member , ALDH-E2 , ALDHI , ALDM

反应种属:

Human, Mouse, Rat

宿主来源:

Goat

实验应用:

ELISA, Sandwich ELISA, WB

靶标/特异性:

This antibody is expected to recognize both reported isoforms (NP_000681.2; NP_001191818.1).

同种型:

IgG

免疫原:

Peptide with sequence C-DETQFKKILGYIN, from the internal region of the protein sequence according to NP_000681.2; NP_001191818.1.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

偶联:

Unconjugated

产品浓度:

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

TBS, 0.5% BSA, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016]

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