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折扣/货期| 货号：GTX27635 | 规格：1mg | 目录价：￥7600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
alpha 1 Antitrypsin antibody (HRP)
别名:
serpin family A member 1 , A1A , A1AT , AAT , PI , PI1 , PRO2275 , alpha1AT , nNIF
反应种属:
Human
宿主来源:
Goat
实验应用:
ELISA, IHC, WB
同种型:
IgG
免疫原:
Alpha 1-Anti-Trypsin collected from human plasma
克隆性:
Polyclonal
克隆号:
纯化方式:
IgG fraction
偶联:
HRP
产品浓度:
10 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
47
产品形式:
Liquid
存储溶液:
20mM Potassium Phosphate, 150mM NaCl, 1% BSA, 0.01% Gentamicin Sulfate.
生产商:
GeneTex
功能与背景:
Alpha 1 Antitrypsin is a plasma protein synthesised in the liver. It consists of a single polypeptide chain and has a molecular weight of 52 kDa. A serine protease inhibitor, its primary function is the protection of lung tissue from the action of neutrophil elastase. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Short peptide from AAT (SPAAT) is a reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE). The average level of alpha 1 Antitrypsin in plasma is 1.3 g/l.
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