Alpha 1 Microglobulin Antibody / AMBP / Bikunin-单抗-深圳欣博盛生物科技有限公司

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Alpha 1 Microglobulin Antibody / AMBP / Bikunin

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V5301SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

Alpha 1 Microglobulin Antibody / AMBP / Bikunin

产品描述:

The AMBP (Alpha-1-Microglobulin/Bikunin precursor) gene encodes a protein precursor, known as AMBP, that is cleaved to produce two distinct proteins, designated Alpha-1-Microglobulin and Bikunin. Alpha-1-Microglobulin, also known as protein HC, is a member of the lipocalin superfamily and is secreted mainly in plasma, urine and cerebrospinal fluid. Thought to have reductase/dehydrogenase activity, Alpha-1-Microglobulin exhibits immunosuppressive properties, such as cytokine secretion and inhibition of antigen-induced lymphocyte cell proliferation, and may be involved in the reduction of biological pro-oxidants. The second protein cleavage product, designated Bikunin and also known as inter-Alpha-trypsin inhibitor light chain, ITI-LC or urinary trypsin inhibitor, is a widely expressed protein that is stored in the granules of human connective tissue mast cells. One of many proteins in the Kunitz-type protease inhibitor family, Bikunin prevents autodigestion by exocrine enzymes, such as trypsinogen and chymo-trypsinogen, and plays a role in the antiinflammatory/antiproteinase immune response. Unlike Alpha-1-Microglobulin, Bikunin is implicated in the pathogenesis of a number of renal diseases, such as urolithiasis.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG2, kappa

免疫原:

A recombinant partial protein sequence (within amino acids 200-353) from the human protein was used as the immunogen for the Alpha 1 Microglobulin antibody.

克隆性:

Monoclonal (mouse origin)

克隆号:

AMBP/4536

纯化方式:

Protein A/G affinity

保存温度:

Aliquot the Alpha 1 Microglobulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

产品形式:

Purified

存储溶液:

1 mg/ml in 1X PBS; BSA free, sodium azide free