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折扣/货期| 货号：GTX52538 | 规格：100μg | 目录价：￥8000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
alpha 2 Macroglobulin antibody [4H44]
别名:
A2M , A2MD , CPAMD5 , FWP007 , S8637 , alpha2macroglobulin , alpha2 macroglobulin , alpha 2 Macroglobulin , alpha-2-macroglobulin
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB
同种型:
IgG1
免疫原:
Human recombinant α -2 macroglobulin
克隆性:
Monoclonal
克隆号:
4H44
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
500 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
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