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折扣/货期| 货号：GTX18061 | 规格：100μg | 目录价：￥6100 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
alpha Actinin 1 antibody [0.T.02]
别名:
ACTN1 , BDPLT15 , actinin alpha 1 , alpha Actinin 1
反应种属:
Human, Mouse, Rat, Xenopus
宿主来源:
Mouse
实验应用:
ICC/IF, IHC-Fr, WB
靶标/特异性:
Recognizes human alpha-Actinin 1 isoform (non-muscle) at 100kD.
同种型:
IgG1
免疫原:
Human alpha-Actinin
克隆性:
Monoclonal
克隆号:
0.T.02
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
103
产品形式:
Liquid
存储溶液:
PBS, 250mM NaCl, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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