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折扣/货期| 货号：GTX57554 | 规格：100μl | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
alpha Synuclein antibody [5C2]
别名:
synuclein alpha , NACP , PARK1 , PARK4 , PD1 , SNCA , alpha Synuclein
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB
靶标/特异性:
Based on internal testing result, this antibody does not cross react with human beta- and gamma-synuclein.This antibody specifically recognizes the NAC domain (61-95aa) of alpha-synuclein.
同种型:
IgG1
免疫原:
The clone 5C2 is derived from hybridization of mouse SP2/2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human alpha-synuclein protein.
克隆性:
Monoclonal
克隆号:
5C2
纯化方式:
Protein G Purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
14
产品形式:
Liquid
存储溶液:
PBS, 10% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
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