官网链接
折扣/货期| 货号：GTX66847 | 规格：100μl | 目录价：￥6500 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AMPK beta 1 antibody [1A7]
别名:
protein kinase AMP-activated non-catalytic subunit beta 1 , AMPK , HAMPKb
反应种属:
Human, Monkey, Mouse, Rat
宿主来源:
Mouse
实验应用:
ICC/IF, IHC-P, IP, WB
同种型:
IgG
免疫原:
Purified recombinant human AMPKβ1 protein fragments expressed in E.coli.
克隆性:
Monoclonal
克隆号:
1A7
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
100mM Tris-Glycine, 150mM NaCl, 50% Glycerol, 0.2% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]
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