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折扣/货期| 货号：GTX79141 | 规格：100μg | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AMPK beta 1 (phospho Ser182) antibody
别名:
AMPK,HAMPKb,PRKAB1,protein kinase AMPactivated noncatalytic subunit beta 1,AMPK beta 1,protein kinase AMP-activated non-catalytic subunit beta 1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P, WB
同种型:
IgG
免疫原:
The antiserum was produced against synthesized phosphopeptide derived from human AMPKbeta1 around the phosphorylation site of serine 182 (S-S-Sp-P-P).
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
30
产品形式:
Liquid
存储溶液:
PBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format), 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]
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