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折扣/货期| 货号：REV-31-1164-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Cyclin B1 (human), Rabbit Monoclonal (RM281)
别名:
CCNB1; G2/Mitotic-specific Cyclin-B1
产品描述:
Cyclins bind to and regulate the activity of the Cyclin dependent protein kinases (CDKs). Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis. It is essential for the control of the cell cycle at the G2/M transition. Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. Cyclin B1 is not ubiquitinated during G2/M phase, resulting in its steady accumulation during G2 phase, followed by abrupt APC-dependent destruction at the end of mitosis. Destruction of Cyclin B1 is required for cell cycle progression. Cyclin B1 is overexpressed in various cancers, including breast, prostate and non-small cell lung cancer.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
This antibody reacts to human Cyclin B1.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to Cyclin B1.
克隆号:
RM281
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-Neurofilament-L (human), Rabbit Monoclonal (RM280)
下一个:anti-Cytokeratin-20 (human), Rabbit Monoclonal (RM283)
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