anti-Cytokeratin-20 (human), Rabbit Monoclonal (RM283)-单抗-深圳欣博盛生物科技有限公司

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anti-Cytokeratin-20 (human), Rabbit Monoclonal (RM283)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1166-00-R100

规格：100 ul

目录价：￥5726

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-Cytokeratin-20 (human), Rabbit Monoclonal (RM283)

别名:

CK20; CK-20; Cytokeratin 20

产品描述:

Cytokeratins are keratin proteins found in the intracytoplasmic cytoskeleton of epithelial tissue (at least 20 different polypeptides). They are an important component of intermediate filaments, which help cells resist mechanical stress. Expression of these cytokeratins within epithelial cells is largely specific to particular organs or tissues. The subsets of cytokeratins which an epithelial cell expresses depends mainly on the type of epithelium, the moment in the course of terminal differentiation and the stage of development. Thus a specific cytokeratin expression profile allows the identification of epithelial cells. Furthermore, this applies also to the malignant counterparts of the epithelia, (carcinomas). Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. Cytokeratin-20 (CK20) is a type I cytokeratin. It is a major cellular protein of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa. Cytokeratin-20 is a useful marker of pancreatic and colorectal cancer. Cytokeratin-20 is also helpful in distinguishing different types of highly related carcinomas, such as renal oncocytomas from renal cell carcinomas. It is often used in combination with antibodies to Cytokeratin-7 (CK7) to distinguish different types of glandular tumour.

宿主来源:

Rabbit

实验应用:

IHC, WB

靶标/特异性:

This antibody reacts to human CK20 (Cytokeratin-20).

同种型:

Rabbit IgG

免疫原:

A peptide corresponding to the C-terminus of human Cytokeratin-20.

克隆号:

RM283