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折扣/货期| 货号：AG-25B-0043-C050 | 规格：50 ug | 目录价：￥2400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-GLUT2 (rat), pAb (IN119)
别名:
Solute Carrier Family 2, Facilitated Glucose Transporter Member 2; SLC2A2; Glucose Transporter Type 2, Liver
产品描述:
GLUT2 belongs to the family of glucose transporters (GLUTs, encoded by the SLC2A genes), which comprises 14 isoforms. GLUT2 has a uniquely low affinity for glucose (Km ~ 17mmol/l), and can also use mannose, galactose and fructose as low-affinity substrates. However, it has a high affinity for glucosamine (Km ~ 0.8mmol/l). GLUT2 is expressed in liver, intestine, kidney and pancreatic islet beta cells, as well as in the central nervous system, in neurons, astrocytes and tanycytes. Physiological studies of genetically modified mice have revealed a role for GLUT2 in several regulatory mechanisms. GLUT2 is also the major glucose transporter in the plasma membrane of hepatocytes. In pancreatic beta cells, GLUT2 is required for glucose-stimulated insulin secretion. In the nervous system, GLUT2-dependent glucose-sensing controls feeding, thermoregulation and pancreatic islet cell mass and function, as well as sympathetic and parasympathetic activities.
宿主来源:
Rabbit
实验应用:
IHC, IP, WB
靶标/特异性:
Recognizes rat GLUT2.
免疫原:
A synthetic peptide corresponding to 10 aa located near the C-terminus of rat GLUT2.
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% Proclin 300.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
促销活动
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